Using the Pulse video service, you can upload and analyze your cardiomyocyte videos captured on any imaging system for automated analysis.
Use your standard multi-well plates. No dyes, no electrodes. Nothing touches your cells except the compounds you’d like to test.
Plate your cells however you’d like, and Pulse will automatically generate measurements for each distinct beating cell or group of cells.
Pulse is the simplest software that I have used to date and I highly recommend using Pulse for individuals who are interested in studying cellular phenotypes of cardiomyocytes. Using Pulse has allowed me and fellow lab members to identify cellular phonotypes that would have been impossible to identify otherwise. One great feature about Pulse is that no additional adjustments to parameters are necessary, which makes it very easy to use for scientists with limited computational background.
Pulse satisfies a significant need in the field of cardiac disease modeling. The high throughput, automated video analysis enables the efficient measurement of contractility in human iPSC-cardiomyocytes from a number of patients with diverse disease background, age group, gender and ethnicity. It also allows the study of therapeutic or cytotoxic compounds in relation to their effect on hiPSC-cardiomyocytes. Pulse is extremely user-friendly for either experienced researchers or starting students.
Using Pulse has allowed me to generate meaningful data related to cardiac physiology in a fraction of the time it took with previous technology. I can test a large number of different conditions with minimal hands-on time and the data will be ready and waiting for me at my convenience.
Pulse offers a simple and user-friendly cloud-based data storage and analysis option. The automated video analysis allows for a detailed understanding of the cell behavior such as functional properties of beating cardiomyocytes in health and disease states.